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329,330 Advances in β-cell genetic engineering, employing methods like clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (hereinafter referred to as Cas9) to modify genes, aim to reduce their immunogenicity or produce local immunomodulatory factors, offering hope for longer-lasting β-cell survival
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Certain conditions, including a personal or family history of thyroid cancer, may make these medications inappropriate
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